Y: The Last Man: Vol 1 by Brian K. Vaughan
This is the first in the series where all the men have been "destroyed" by a mysterious source that the women and Yorick "The Last Man" Brown call "The Plague. Yorick has teamed up with a secret agent, 355, from a troop called The Culper Ring. They find a bio-engineer and try to clone Yorick, but the lab burns down and their journey starts to find the second lab. I thought this book was very exciting. It had a lot of action.